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Nuclear localization of an aggregate of a short, Q20, poly(Q) peptide is just as toxic as that of a long poly(Q) peptide, supporting the notion that the influence of poly(Q) repeat length on disease risk and age of onset is at the level of aggregation efficiency

Figure 3 Figure 4 4.1 Weight-dependent (indirect) mechanism of action Central-mediated feeding suppression and weight loss remain the most classic indirect mechanism of PYY (3-36)

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Juan: en 2017 se aprueba para ribetes, en 2021 se aprueba para rdida de peso, relativamente nuevo, lo otro que estoy viendo es que estoy con muchos pacientes que quieren usarlo por el resto de su vida